Analgesic Value of Adductor Canal vs Femoral Block After Total Knee Arthroplasty

Duke University

Status: Completed

Conditions: Osteo Arthritis Knee

Treatments: Procedure: Sham comparator: saline; Procedure: Active comparator: chloroprocaine

Study type: Interventional

Funder types: Other

Identifiers

NCT03395990

PRO00067430

Details and patient eligibility

About

An observational study of the effect of femoral nerve block in addition to an adductor canal block for pain following total knee arthroplasty.

Full description

Subjects undergoing total knee arthroplasty will receive a preoperative adductor canal block with continuous catheter. Following a standardized general anesthetic for the procedure, subjects will be asked to rate their pain using the NRS-11 pain scale in the recovery room. Once the pain is reported at a 5/10 or above, a femoral nerve block will be performed using either 2% chloroprocaine or saline placebo (randomized). Pain scores are then evaluated over the next 30 minutes by a blinded investigator to determine if the femoral block adds any additional analgesic benefit over an adductor canal block.

Enrollment: 16 patients

Sex: All

Ages: 56 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients scheduled for elective total knee arthroplasty
• ASA Physical Status I-III
• BMI 18-40 kg/m2

Exclusion criteria

• Inability to cooperate with protocol
• Inability to understand or speak English
• Allergy to any local anesthetic
• Chronic opioid consumption/abuse (30 or more morphine mg equivalents/day)
• Contraindication to adductor canal or femoral nerve block

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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16 participants in 2 patient groups

chloroprocaine

Active Comparator group

Description:

15 ml of 2% chloroprocaine via a femoral nerve block technique

Treatment:

Procedure: Active comparator: chloroprocaine

saline

Sham Comparator group

Description:

15 ml of 0.9% saline via a femoral nerve block technique

Treatment:

Procedure: Sham comparator: saline