Analgetic Effect of Nitrousoxide-oxygen Inhalation for Dental Treatment of Children

University of Aarhus

Status: Completed

Conditions: Dental Pain; Skin Sensitivity to Electric Stimulation; Muscle Sensitivity to Pressure

Treatments: Drug: Atmospheric air; nitrousoxide-oxygen; Drug: Nitrousoxide-oxygen and atmospheric air

Study type: Interventional

Funder types: Other

Identifiers

NCT01022294

M-20070261

Details and patient eligibility

About

To assess the analgetic effect of nitrousoxide-oxygen inhalation on pain perception in 12-15 years old children from 1) the dental pulp; 2) the masseter muscle; 3) the skin on the upper lip

Full description

The present study is a randomized, cross-over blinded study on the analgetic effect of nitrousoxide-oxygen on sensitivity of the dental pulp, the skin and muscles.

It is conducted in healthy 12-15 year old Danish children attending public schools in the municipality of Aarhus, Denmark

Enrollment: 56 patients

Sex: All

Ages: 12 to 15 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• ASA-groups I or II
• 12-15 year of age
• sound upper central incisors

Exclusion criteria

• difficulties breathing through the nose
• pregnancy
• trauma to test teeth

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Triple Blind

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56 participants in 2 patient groups

Arm 1

Experimental group

Description:

Inhalation of nitrousoxide-oxygen during the first experimental session; inhalation of atmospheric air during the second session

Treatment:

Drug: Nitrousoxide-oxygen and atmospheric air

Arm 2

Experimental group

Description:

Inhalation of atmospheric air during the first experimental session; inhalation of nitrousoxide-oxygen during the second session

Treatment:

Drug: Atmospheric air; nitrousoxide-oxygen