Analgetic Effect of Two Solutions of Intracameral Anesthesia During Cataract Surgery in Patients

Medical University of Lublin

Status: Completed

Conditions: Ophthalmological Disorder; Cataract; Analgesia

Treatments: Diagnostic Test: Slit-lamp biomicroscopy; Drug: lignocaine; Procedure: Intraocular lens implantation; Diagnostic Test: Best corrected visual acuity measurment; Behavioral: Visual Analog Scale for Pain; Behavioral: Brief Pain Inventory-short form; Procedure: Phacoemulsyfication

Study type: Observational

Funder types: Other

Identifiers

NCT04166578

002

Details and patient eligibility

About

Purpose: The aim of the study was to compare the analgetic effect of two solutions of intracameral anesthesia in patients undergoing cataract surgery and assess the factors influencing the patients' postoperative activities.

Methods: In this prospective, single-blind, randomized study, a group of 62 patients undergoing cataract surgery received Mydrane (Mydrane group) or a combination of 1% solution of lignocaine and 0.025% solution of adrenalin (reference group) as an intraocular anesthetic. The analgetic effect of these two anesthetic methods was evaluated using psychological tools - Visual Analog Scale for Pain (VAS Pain) and Brief Pain Inventory-short form (BPI) on the next day after the surgery.

Enrollment: 62 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age above 18 years
• best corrected visual acuity (BCVA) of 0.2 logMAR or worse
• and agreement for taking part in the study

Exclusion criteria

• depressive disorder or expected compliance problems (known psychiatric disease)
• epilepsy
• ongoing treatment with hypnotics or psychotropic drugs (including opioids) within a week before admission
• daily analgesic treatment
• intake of additional rescue medications due to the pain after surgery
• omitting postoperative visit
• no consent to complete the survey
• The patients who later needed additional medications for pain relief

Trial design

62 participants in 2 patient groups

Mydrane group

Description:

Patients were randomly selected to the group receiving intracameral 0.2 ml Mydrane (a solution of 1% lidocaine and 0.025% of adrenaline ) during phacoemulsification.

Treatment:

Behavioral: Brief Pain Inventory-short form

Behavioral: Visual Analog Scale for Pain

Drug: lignocaine

Diagnostic Test: Best corrected visual acuity measurment

Diagnostic Test: Slit-lamp biomicroscopy

Procedure: Intraocular lens implantation

Procedure: Phacoemulsyfication

Reference group

Description:

Patients were randomly selected to the group receiving intracameral a combination of intracameral solution of lignocaine 1% and adrenalin 0.025% (0.2 ml) during phacoemulsification.

Treatment:

Behavioral: Brief Pain Inventory-short form

Behavioral: Visual Analog Scale for Pain

Drug: lignocaine

Diagnostic Test: Best corrected visual acuity measurment

Diagnostic Test: Slit-lamp biomicroscopy

Procedure: Intraocular lens implantation

Procedure: Phacoemulsyfication