Analysis of Changes in Blood Glucose Spinal Epidural Nerve Block with Steroids in Patients with Low Back Pain

Sung Hyun Lee

Status: Not yet enrolling

Conditions: Glucose Level Change

Treatments: Procedure: Epidural steroid injection (ESI)

Study type: Interventional

Funder types: Other

Identifiers

NCT06818617

2024-12-014

Details and patient eligibility

About

This study aims to investigate the effect of different doses of dexamethasone used in epidural nerve block procedures on blood sugar levels. Patients with spinal conditions such as stenosis or disc herniation will be enrolled. Blood glucose and HbA1c levels will be measured before the procedure, and participants will use continuous glucose monitoring devices for 2-3 days before the procedure. They will be randomly assigned to one of three groups: no dexamethasone, 5mg dexamethasone, or 7.5mg dexamethasone. Blood glucose will be monitored for one week after the procedure, and follow-up will be done two weeks later to assess pain and blood sugar data. This study will help determine how steroid doses affect blood sugar, especially in elderly patients, and provide more accurate information than previous studies.

Enrollment: 60 estimated patients

Sex: All

Ages: 19 to 90 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• patients need to epidural steroid injection for treating back pain
• patients diagnosed with diabetes or prediabetes.

Exclusion criteria

• Patients with poorly controlled blood sugar.(HbA1c>8.5)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Double Blind

---

60 participants in 3 patient groups

dexamethasone dose-0

Active Comparator group

Treatment:

Procedure: Epidural steroid injection (ESI)

dexamethasone dose 5.0

Active Comparator group

Treatment:

Procedure: Epidural steroid injection (ESI)

dexamethasone dose-7.5

Active Comparator group

Treatment:

Procedure: Epidural steroid injection (ESI)