Analysis of Effects of High-intensity Physical Exercise in Subjects With Dialyzed Chronic Kidney Disease and in Conservative Treatment (TONE)

Casa di Cura Dott. Pederzoli

Status: Enrolling

Conditions: Chronic Kidney Disease

Treatments: Other: Exercise; Other: control

Study type: Interventional

Funder types: Other

Identifiers

NCT07438002

573CET

Details and patient eligibility

About

This study aims to analyze the effects of physical activity in patients with chronic kidney disease undergoing dialysis or conservative treatment. Patients will be randomized into two groups: combined exercise (high-intensity aerobic resistance + strength training) and control group

Enrollment: 50 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Signature of the informed consent
• Patients with CKD stage 1 to 5 under conservative treatment
• Patients undergoing chronic hemodialysis for at least 3 months
• Age ≥ 18

Exclusion criteria

• Severe cardiovascular disease (NYHA class IV or hypertension class III)
• TIA or myocardial ischemia within the last three months
• Anatomical limitations
• Health conditions detected during the stress test (CPET)

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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50 participants in 2 patient groups

combined exercise

Experimental group

Description:

participants will undergo a combined endurance and resistance exercise training

Treatment:

Other: Exercise

control group

Active Comparator group

Description:

participants performs outcome measures sessions only, including blood sample collection.

Treatment:

Other: control