Analysis of Endoloops, Endostaples and Endoclips for Closing the Appendiceal Stump During Laparoscopic Appendectomy

University Hospital Dubrava

Status: Completed

Conditions: Laparoscopic Surgery; Appendicitis Acute

Treatments: Device: Technique used for closing the appendiceal stump

Study type: Interventional

Funder types: Other

Identifiers

NCT04083313

UHDubrava1

Details and patient eligibility

About

In this randomized control trial the patients with acute appendicitis will be divided in three groups according to the management of the appendiceal stump(Endostapler, Endoloop or Endoclip). Pre-, peri- and postoperative data will be analysed.

Full description

Acute appendicitis is the most common indication for intraabdominal emergency surgery, and appendectomy is one of the most commonly performed procedures in abdominal surgery. Today laparoscopic appendectomy (LA) has the status of a ''Gold Standard'' treatment, and it is accepted as the treatment of choice for acute appendicitis.There are several ways of closing the appendiceal stump.An inadequate closure of the appendiceal stump can lead to morbidity of operated patients. The aim of this study is to assess the efficiency of different closure techniques by focusing on the intraoperative and postoperative complications.The patients will be divided into three groups based on the technique used for appendiceal stump closure, whether it is Endoloop, Endostapler or Endoclip. In the patients included in the study the investigators will analyse demographic data, peroperative laboratory values, clinical data and treatment outcomes. Also, the histopathological findings of the specimens and perioperative and postoperative complications will be analysed.

Enrollment: 300 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with clinically and radiologically(Ultrasound) verified appendicitis

Exclusion criteria

• Patients converted from laparoscopy to open surgery

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

300 participants in 3 patient groups

Endoloop

Active Comparator group

Description:

Patients in which appendiceal stump was ligated using Endoloop

Treatment:

Device: Technique used for closing the appendiceal stump

Endostapler

Active Comparator group

Description:

Patients in which appendiceal stump was ligated using Endostapler

Treatment:

Device: Technique used for closing the appendiceal stump

Endoclip

Active Comparator group

Description:

Patients in which appendiceal stump was ligated using Endoclip

Treatment:

Device: Technique used for closing the appendiceal stump