Analysis of Extraperitoneal Rectal Neoplasms Between 3D Endorectal Ultrasonography and Magnification Chromoendoscopy

University of Sao Paulo

Status: Unknown

Conditions: Rectal Cancer Stage I; Rectal Cancer

Treatments: Procedure: three-dimensional endorectal ultrasonography

Study type: Interventional

Funder types: Other

Identifiers

NCT04527939

9076079

Details and patient eligibility

About

ERUS-3D and CMI demonstrated good diagnostic accuracy in parietal staging of rectal extraperitoneal neoplasms, however with greater efficiency of the endoscopic method. The association of studies can improve diagnostic efficacy and influence the most appropriate approach.

Full description

Larger lesions present less chance of deep parietal invasion. The methods show moderate agreement with each other for lesion size and distance from the anal verge and good agreement for the rectal wall percentage of involvement. Circumferential or almost circumferential lesions have a greater chance of postoperative stenosis. Patients with more advanced lesions on AP who underwent radical resections had lower overall survival.

Enrollment: 70 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: patients with diagnosis of mid or distal rectum neoplasms stage 1 -

Exclusion Criteria: advanced rectal cancer (stage II, III or IV)

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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70 participants in 2 patient groups

three-dimensional endorectal ultrasonography

Active Comparator group

Description:

three-dimensional endorectal ultrasonography

Treatment:

Procedure: three-dimensional endorectal ultrasonography

magnification chromoendoscopy.

Sham Comparator group

Description:

magnification chromoendoscopy.

Treatment:

Procedure: three-dimensional endorectal ultrasonography