Analysis of Immediate Urinary Continence Predictors After RS-RARP

Fujian Medical University (FJMU)

Status: Active, not recruiting

Conditions: Retzius-sparing Robot-assisted Radical Prostatectomy; Prostate Cancer (Post Prostatectomy); Urinary Continence

Treatments: Procedure: Retzius-sparing robot-assisted radical prostatectomy

Study type: Observational

Funder types: Other

Identifiers

NCT06850116

MRCTA,ECFAH OfFMUI2025]002

Details and patient eligibility

About

This study is a retrospective, single-center clinical trial. It aims to retrospectively analyze the immediate postoperative urinary continence recovery in prostate cancer patients who underwent Retzius-sparing robot-assisted radical prostatectomy in the investigators' center. Based on the general conditions of patients, relevant perioperative clinical indicators, and parameters related to the sphincter and prostate gland measured by MRI, it explores the influencing factors of immediate urinary continence recovery after Retzius-sparing robot-assisted radical prostatectomy in prostate cancer patients and constructs a relevant prediction model, thereby providing clinical guidance value for predicting immediate postoperative urinary continence recovery.

Enrollment: 400 estimated patients

Sex: Male

Volunteers: No Healthy Volunteers

Inclusion criteria

• Prostate cancer diagnosed by prostate biopsy and underwent Retzius-sparing robot-assisted radical prostatectomy in the investigators' hospital.
• Received plain and contrast-enhanced pelvic or prostate MRI examinations before surgery.
• Eastern Cooperative Oncology Group (ECOG) performance status score between 0 and 1.
• Complete clinicopathological data.
• In good general condition, without infections, autoimmune diseases, hematological diseases or other malignant tumors.
• Complete postoperative follow-up data, with a postoperative follow-up time of no less than 6 months.

Exclusion criteria

• The patient has surgical contraindications.
• The patient has contraindications for MRI examination.
• Preoperative presence of congenital urinary system malformations, urinary incontinence or severe lower urinary tract symptoms, and with a history of urinary catheter or previous transurethral resection of the prostate (TURP) surgery.
• Having received neoadjuvant treatments that may affect the results of this study, such as radiotherapy or hormonal therapy.
• The patient has other concurrent malignant tumors.
• The patient has delayed extubation (> 14 days).
• The patient's clinical, imaging and pathological data are incomplete or the patient is lost to follow-up.

Trial design

400 participants in 1 patient group

The Retzius-sparing robot-assisted radical prostatectomy group

Description:

In 2010, Italian urologist Dr Bocciardi carried out the first clinical practice of separation and resection of the prostate via the vesicorectal fossa, and this new surgical procedure was called Retzius-sparing Robotic Assisted Radical Prostatectomy (RS-RARP). In recent years, the posterior approach extrafascial technique of RS-RARP which has been used to widely resect the prostate and its surrounding fascia and neurovascular bundles, compared with RS-RARP, has been proposed to provide more complete resection of the tumour and reduce the rate of positive margins. The patients are included into the Retzius-sparing robot-assisted radical prostatectomy group group who undergo the posterior approach extrafascial technique of RS-RARP.

Treatment:

Procedure: Retzius-sparing robot-assisted radical prostatectomy