Analysis of Immune Response In Bacterial Infection of Obese Subject (ARIIBO)

Versailles Hospital

Status

Completed

Conditions

Obesity

Treatments

Biological: blood analysis

Study type

Interventional

Funder types

Other

Identifiers

NCT02882568

P15/19_ARIIBO

Details and patient eligibility

About

Improve knowledge of the immune response to sepsis in obese patients. Define immunological and genetic prognostic factors of severe infections which can motivate a change in the therapeutic attitude

Enrollment

15 patients

Sex

All

Ages

18 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

between18 and 80 years
obesity: BMI > 30
presumed bacterial infection:
- pneumonitis (documented or probably)
- pyelonephritis / acute prostatitis
- soft tissue / skin infection (except for bedsore)
- cholecystitis / angiocholitis
- meningitis
- clostridium colitis
- surgical site infection
signed consent

Exclusion criteria

patients with viral, parasitic or mycotic documented infection
patients with bacterial infection with treatment> 4 weeks (ex. endocarditis; osteo- articular infections)
patients with prior antibiotic treatment (< 14 days)
intensive care unit patients
patients with a history of cancer or malignant hematological disease within the 5 previous years that is currently clinically significant (non metastatic prostatic and basocellular malignancy are excluded)
patients with systemic disease
Known diagnosis of human immunodeficiency infection (DICV, HIV...)
immunosuppression treatment during last month including corticotherapy
pregnancy
3 months follow up not possible
non signed consent