Analysis of Individual Activity at the Time of Aortic Rupture in Patients With Abdominal Aortic Aneurysms

U

University Hospital Augsburg

Status

Enrolling

Conditions

Aortic Aneurysm

Treatments

Behavioral: Bahaviour at the time of an aortic aneurysm rupture

Study type

Observational

Funder types

Other

Identifiers

NCT06365138
Aortic Rupture

Details and patient eligibility

About

It is currently unclear what activities aneurysms are involved in at the time of rupture. The aim of the study is to determine the activity performed at the time of aneurysm rupture.

Full description

The scientifically proven risk factors that significantly favor the rupture of an aortic aneurysm are female gender, the maximum diameter of the aortic aneurysm and the patient's current smoking status. However, no analysis of the occupation performed at the time of aortic rupture of an abdominal aortic aneurysm has yet been carried out. High arterial systolic blood pressure can promote aortic rupture. Blood pressure peaks can occur during physical exertion, for example when lifting heavy loads or during defecation. Patients with an existing intact aortic aneurysm are currently advised to avoid such behaviors as a preventive measure. This includes, among other things, the practice of strength training or certain types of sport. This can subsequently lead to a reduction in quality of life, although this cannot currently be substantiated by scientific data. There is also no current guideline recommendation in this regard. Furthermore, the role of stress and / or emotionally stressful events in connection with the occurrence of aortic ruptures has not yet been recorded in the literature. There is work on this in connection with aortic dissections, which postulates that an increase in emotional or psychological stress can lead to acute hypertension, which can cause a previously damaged aorta to rupture. A similar pathomechanism would also be conceivable for the rupture of aortic aneurysms. There are indications that, in addition to gender-specific differences in the occurrence of aortic ruptures, there is also a different risk of rupture based on certain pre-existing conditions, dietary habits and age.

Enrollment

500 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • inclusion of all patients with ruptured aortic aneurysm in Augsburg University Hospital
  • Written consent to participate in the study by the patient or their legal representative

Exclusion criteria

Lack of consent

Trial contacts and locations

1

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Central trial contact

Yvonne Gosslau, MD; Tobias Warm, MD

Data sourced from clinicaltrials.gov

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