Analysis of Line-Field Confocal Optical Coherence Tomography (LC-OCT) in Characterization of Gingival Systemic Health, Gingivitis and Periodontitis (Perio-LC-OCT)

University of Catania

Status: Invitation-only

Conditions: Gingival Diseases

Treatments: Device: Line-Field Confocal Optical Coherence Tomography (LC-OCT)

Study type: Interventional

Funder types: Other

Identifiers

NCT06831487

2024-3307

Details and patient eligibility

About

The aim of the study is to identify tissue changes among healthy patients, patients with gingivitis and with periodontitis before and after treatment, by analyzing tissues changes through Line-Field Confocal Optical Coherence Tomography (LC-OCT)

Full description

The tissue changes among healthy patients, patients with gingivitis and with periodontitis before and after treatment, by analyzing tissues changes through Line-Field Confocal Optical Coherence Tomography (LC-OCT) will be evaluated through changes on epithelium before and after non surgical periodontal treatment

Enrollment: 60 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosis of gingivitis or periodontitis by the presence of elevated bleeding or probing index or probing pocket depth

Exclusion criteria

• Smoking
• Any systemic diseases that could influence the gingival structure

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 3 patient groups, including a placebo group

Analysis of Line-Field Confocal Optical Coherence Tomography (LC-OCT) in gingivitis

Active Comparator group

Description:

Analysis of tissue changes pre and post non surgical periodontal treatment using Line-Field Confocal Optical Coherence Tomography (LC-OCT) in gingivitis patients

Treatment:

Device: Line-Field Confocal Optical Coherence Tomography (LC-OCT)

Line-Field Confocal Optical Coherence Tomography (LC-OCT) periodontitis

Active Comparator group

Description:

Line-Field Confocal Optical Coherence Tomography (LC-OCT) in periodontitis patients

Treatment:

Device: Line-Field Confocal Optical Coherence Tomography (LC-OCT)

Line-Field Confocal Optical Coherence Tomography (LC-OCT) - Healthy patients

Placebo Comparator group

Description:

Analysis of Line-Field Confocal Optical Coherence Tomography (LC-OCT) in healthy patients

Treatment:

Device: Line-Field Confocal Optical Coherence Tomography (LC-OCT)