Analysis of Oxidative Stress Biomarkers and Their Determinants in ART-experienced PLWH (4477)

Institute of Hospitalization and Scientific Care (IRCCS)

Status: Enrolling

Conditions: HIV Infections

Treatments: Other: blood sampling

Study type: Observational

Funder types: Other

Identifiers

NCT05760495

4477

Details and patient eligibility

About

The project aims to assess the level of oxidative stress biomarkers in HIV patients on effective antiretroviral treatment in correlation with other therapeutic, clinical, and viro- immunological parameters. The analysis aims to better characterize the patient on treatment through an innovative approach based on two specific tests for complementary assessment of total oxidant and anti-oxidant plasma capacity.

Enrollment: 543 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ART-treated PLWH
• HIV-1 RNA< 50 copies/mL
• Stable ART therapy (at least 48 weeks)
• Signature of informed consent for study participation

Exclusion criteria

• none

Trial design

543 participants in 1 patient group

Single arm

Description:

ART-experienced PLWH

Treatment:

Other: blood sampling