Analysis of Risk Factors for High Intraocular Pressure and Retinal Detachment Recurrence After Vitrectomy with Silicone Oil Tamponade in Retinal Detachment Patients

Chongqing Medical University

Status: Enrolling

Conditions: Rhegmatogenous Retinal Detachment

Treatments: Diagnostic Test: retinal recovery status; Diagnostic Test: Intraocular pressure

Study type: Observational

Funder types: Other

Identifiers

NCT06826573

2024-130-01

Details and patient eligibility

About

This study is a retrospective study. Patients who visited the ophthalmology clinic of the First Affiliated Hospital of Chongqing Medical University between September 1, 2024, and December 31, 2025, will be screened according to the inclusion and exclusion criteria mentioned below. After obtaining informed consent, clinical data of the subjects will be collected. The surgical procedure will involve "vitrectomy + retinal laser photocoagulation + retinal reattachment + silicone oil tamponade (+ cataract extraction + intraocular lens implantation)." Observation indicators will be recorded at various time points postoperatively: 1 day, 1 week, 1 month, 3 months, 6 months, and before silicone oil removal. Any emergent events occurring during the trial will be treated accordingly. Finally, data will be statistically analyzed to identify risk factors for high intraocular pressure and retinal detachment recurrence in patients with rhegmatogenous retinal detachment.

Enrollment: 65 estimated patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 1. Diagnosed with "rhegmatogenous retinal detachment". 2. Aged over 18 years old, with normal mental and psychological status, regardless of gender.

  2. Intraocular pressure of both eyes is less than 21 mmHg before surgery, and having no personal or family history of glaucoma.

  3. Cup - to - disc ratio (C/D) in fundus examination is less than 0.5 for both eyes.

  4. Those who understand the purpose of this study, sign the "Informed Consent Form" and have a high degree of compliance.

Exclusion criteria

• 1. Those with high intraocular pressure before surgery and suffering from ophthalmic diseases such as glaucoma; 3. Those with acute or chronic systemic infections and hematological diseases; 4. Those with a history of mental and psychological diseases; 5. Those with incomplete survey data or unable to cooperate with this research. 5. Those with traumatic rhegmatogenous retinal detachment; 6. Those with active ocular infectious lesions in either eye; 7. Those with severe refractive media opacity (such as corneal nebula, corneal leukoma) in the target eye, which affects imaging examinations during postoperative follow - up.

8. Those with a history of congenital structural abnormalities in the target eye; 9. Those who have undergone vitrectomy for other vitreoretinal diseases in the target eye before screening; 10. Those whom the researchers consider unfit to participate in this clinical trial.

Trial design

65 participants in 4 patient groups

group 1

Description:

Subjects who exhibit elevated intraocular pressure during the follow-up period.

Treatment:

Diagnostic Test: Intraocular pressure

group 2

Description:

Subjects with normal intraocular pressure during the follow-up period.

Treatment:

Diagnostic Test: Intraocular pressure

group 3

Description:

Subjects who experience retinal detachment recurrence during the follow-up period.

Treatment:

Diagnostic Test: retinal recovery status

group 4

Description:

Subjects who do not experience retinal detachment recurrence during the follow-up period.

Treatment:

Diagnostic Test: retinal recovery status