Analysis of the Causes of Redo Pull-through for Recurrent Constipation and the Risk Factors Affecting the Prognosis of the Hirschsprung's Disease and Allied Disorders

Feng Jiexiong

Status: Completed

Conditions: Surgery; Pediatric ALL

Study type: Observational

Funder types: Other

Identifiers

NCT06175598

TJ-IRB20230739

Details and patient eligibility

About

The goal of this observational study is to conducted a comprehensive analysis of the factors contributing to redo- Pull-through surgery for constipation recurrence in Children who are suffering from Hirschsprun' s disease (HSCR) and its allied disorders (ADHD) . The main question[s] it aims to answer are:

1. Our study focused on the treatment and prognosis of these conditions, drawing upon 16 years of patient data and clinical experiences"
2. What are the key risk factors affecting the prognosis of recurrent constipation patients undergoing repeat PT?

Enrollment: 79 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Patients admitted to the department of pediatric surgery at Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, between January 2005 and December 2021;
2. HSCR and ADHD patients admitted due to "constipation recurrence" and requiring redo-PT.

Exclusion criteria

1. Patients undergoing staged surgeries or undergoing internal sphincterotomy;
2. Patients with concomitant severe congenital anomalies such as Down syndrome; (3) Patients with incomplete postoperative follow-up data after redo-PT.

Trial design

79 participants in 5 patient groups

Acquire Aganglionosis (AA)

Intestinal Dysmotility (ID)

Anastomotic Complications (AC)

Intestinal Neurodevelopmental Impairment (INI)

Incomplete Resection of Affected Intestinal Segments (IRAIS)