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Analysis of The Outcomes of Therapeutic Photorefractive Keratectomy Combined With Prophylactic Accelerated Cross-Linking (PRK-Plus), for Treatment of Thin Suspicious Cornea

F

Fayoum University

Status

Not yet enrolling

Conditions

Thin Suspicious Cornea

Treatments

Procedure: PRK PLUS

Study type

Interventional

Funder types

Other

Identifiers

NCT07277348
PRK PLUS in thin cornea

Details and patient eligibility

About

analyze the outcomes of therapeutic photorefractive keratectomy combined with prophylactic accelerated cross-linking (PRK-Plus), for treatment of thin suspicious cornea

Enrollment

60 estimated patients

Sex

All

Ages

18 to 40 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  1. CCT less than 490 microns

  2. K mean more than 46 and/or K max more than 47.

  3. Astigmatism cylinder >1.5 D.

  4. D value of Belin/Ambrósio Module > 1.6

  5. inferior- superior asymmetry or bow-tie pattern with skewed radial axes on tangential maps and abnormal changes on (BAD).

  6. Asymmetry topography between 2 eyes, even if neither eye"s topographic pattern is in itself decidedly abnormal.

  7. Any significant skewed radial axis with or without inferior steepening, or one diopter or more of inferior steepening in some areas but an I-S value of ,1.4,7.

  8. young patients with against-the-rule astigmatic patterns.

  9. a PTA value 40% if calculated.

  10. Abnormal Topographic Patterns

  11. K2 reading of corneal back surface less than [-7].

  12. D Value of CSTP > 2.5 in Belin/Ambrósio curve

  13. We look at values within the central 5 mm circle; the map should be displayed in the BFTE float mode with an estimated area of 8 mm of diameter:

    • Elevation values on the front surface values > +12 μ
    • Elevation values on the back surface values >+15 μ.
    • If there is any isolated island on either front or back surfaces (in the BFS float mode)

Exclusion criteria

  1. Eyes diagnosed with KC.
  2. CCT less than 450 microns

Trial design

Primary purpose

Treatment

Allocation

Non-Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

60 participants in 2 patient groups

PRK PLUS
Experimental group
Description:
PRK PLUS
Treatment:
Procedure: PRK PLUS
Follow up group
No Intervention group
Description:
follow up with pentacam

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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