Analysis of the Pulmonary Microbiome

University Magna Graecia

Status: Enrolling

Conditions: Microbial Colonization; Pneumonia; Microbial Disease

Treatments: Procedure: Bronchoscopy

Study type: Observational

Funder types: Other

Identifiers

NCT06274931

373

Details and patient eligibility

About

The purpose of the protocol is to study the pulmonary microbiome in patients who develop pneumonia.

Full description

The purpose of the protocol is to study the pulmonary microbiome in patients who develop pneumonia with severe acute respiratory failure, requiring admission to the Intensive Care Unit, and to compare it with that of patients diagnosed with pneumonia but who do not develop severe acute respiratory failure and subsequent admission to the intensive care unit.

Enrollment: 30 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with acute respiratory failure
• Patients with suspect of pneumonia

Exclusion criteria

• pregnancy
• age < 18 years

Trial design

30 participants in 3 patient groups

ICU patients

Description:

Patients admitted to the Intensive Care Unit with a diagnosis of acute respiratory failure

Treatment:

Procedure: Bronchoscopy

non ICU patients

Description:

Outpatient patients with a diagnosis of pneumonia

Treatment:

Procedure: Bronchoscopy

Controls

Description:

In the control group, an alveolar bronchial lavage was performed directly on lung tissue taken from deceased individuals who did not have any known lung pathologies.