Analysis of the Variation of the Retinal Vascularization After a Prolonged Effort (MARETINE)

Fondation Ophtalmologique Adolphe de Rothschild

Status: Completed

Conditions: Retinal Vascular Disorder; Sport Injury

Treatments: Diagnostic Test: Blood pressure measurement; Diagnostic Test: Color retinography; Diagnostic Test: OCT-A

Study type: Observational

Funder types: NETWORK

Identifiers

NCT03864380

MMT_2018_10

Details and patient eligibility

About

The cardiovascular parameters of prolonged physical exercice have been studied, but very little data is available about the retinal vascularization.

The eye allows in vivo visualization of micro-vascularisation and is considered as an excellent marker of general vascular condition.

The marathon is an intense and prolonged exercise (running 42.195 km) in aerobic environment. Thus the investigators propose to study the vascular parameters of the retina, before and after this physical exercise.

This will allow : 1) to collect information on the physiology of the retinal vascularization to prolonged effort, 2) to detect any retinal damage (haemorrhages, edema, occlusion ...), not known to date.

The results may highlight vascular effects related to retinal hypoxia (venous tortuosity, haemorrhage, venous occlusion, hypoxic edema). Furthermore the results may urge prevention in this sport more and more democratized.

the investigators hypothesized that prolonged physical exercice causes a change in retinal vascularization.

Enrollment: 29 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Person registered at the 2019 Paris Marathon

Exclusion criteria

• Ophthalmological disorders making access to the fundus impossible for both eyes

Trial design

29 participants in 1 patient group

Person running a marathon

Description:

Exams performed before (1 month maximum) and after the marathon (1 hour maximum) : Color retinography Optical Coherence Tomography - Angiography (OCT-A) Blood pressure measurement

Treatment:

Diagnostic Test: Color retinography

Diagnostic Test: OCT-A

Diagnostic Test: Blood pressure measurement