Analyzing the Composition of Tears and Blood for Discovery of Novel Signatures of Aggressive Prostate Cancer

University of Arkansas

Status: Active, not recruiting

Conditions: Prostate Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT01514669

133719

Details and patient eligibility

About

The purpose of this research study is to compare profiles in the blood and tears of patients with and without prostate cancer with the goal of developing a method of separating men with aggressive and non-aggressive disease.

Enrollment: 75 estimated patients

Sex: Male

Ages: 35 to 85 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Male, 35-85 years old
2. Patients who present for the evaluation of an abnormal exam or test (elevated PSA, abnormal DRE, etc.)
3. Patients who present for the evaluation of a palpable nodule or induration on prostate exam
4. Patients who meet the requirements of Group 1, 2, or 3 of the protocol

Exclusion criteria

1. Patient < 35 or > 85 years of age
2. Concurrent eye infection or trauma, including active conjunctivitis
3. Abnormal production of tears (too much or too little)
4. Any other conditions the PI or staff feels will not fulfill the criteria for study entry or will place the subject in a harmful environment
5. Atypia on prostate biopsy report

Trial design

75 participants in 1 patient group

No treatment

Description:

No Tx, this is observational