Analyzing the Composition of Tears to Identify Cancer (ACT)
Status and phase
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Treatments
Details and patient eligibility
About
This study will further evaluate the use of protein identification or protein pattern (signature) found in tears. We hypothesize that differences exist between the protein profile in tear fluid from patients with versus without cancer.
Full description
Specifically, this study will compare the protein profile in tear fluid from patients with breast, ovarian or colon cancer versus "normal male and female patients" for differences that show promise as a diagnostic indicator. If such differences can be found, then their diagnostic potential will be assessed and developed further in a subsequent study. The long-term goal of this project will be to develop a screening tool for the detection of breast and/or other cancers.
Enrollment
Sex
Ages
Volunteers
Inclusion criteria
- Female or male, 18-100 years old
- Patients who present for a routine check-up
- Patients who present for the evaluation of an abnormal exam or test (mammogram, ultrasound, MRI, PET, etc.)
- May or may not have a mass present
- Patients who present for the evaluation of a palpable lump or mass
- Patients may be pre or post biopsy for a mass, as long as there is a portion of the mass remaining
Exclusion criteria
- Patient < 18 y/o or > 100 y/o
- Concurrent eye infection or trauma
- Active conjunctivitis
- Abnormal production of tears (too much or too little)
Trial design
Primary purpose
Allocation
Interventional model
Masking
150 participants in 1 patient group
Trial contacts and locations
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Data sourced from clinicaltrials.gov
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