Anatomical Location and Metastasis Pattern of Intrapulmonary Lymph Nodes in NSCLC (ECTOP-1010)

Fudan University

Status: Enrolling

Conditions: Non-small Cell Lung Cancer; Carcinoma

Treatments: Procedure: pulmonary lobectomy

Study type: Observational

Funder types: Other

Identifiers

NCT05094882

ALMPILN

Details and patient eligibility

About

This is a clinical trial from Eastern Cooperative Thoracic Oncology Project (ECTOP), numbered as ECTOP-1010. Anatomical Location and Metastasis Pattern of Intrapulmonary Lymph Nodes (Group 11-13) in Non-small Cell Lung Cancer: a Multi-center, Prospective observational Clinical Trial

Full description

Patients would be evaluated whether meet the criteria as clinical stage T1 non-small Cell Lung Cancer. Then, he/she would receive lobectomy. Finally, the detailed anatomical location of group 11-13 would be recorded immediately after surgery and their metastasis pattern would be explored in the follow-up period.

Enrollment: 500 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Preoperative examination showed patients with clinical T1 peripheral non-small cell lung cancer (NSCLC);
2. The lesion is located in a single lung segment or between two adjacent lung segments;
3. Perform radical lobectomy;
4. The preoperative examination did not reveal unresectable lymph nodes;
5. Have not received any other tumor-related treatments (including chemotherapy, radiotherapy, targeted therapy, immunotherapy, etc.) before surgery;
6. No malignant tumor history;
7. No contraindications to surgery (ECOG score 0-1 points);

Exclusion criteria

1. Pathology revealed patients with non-T1 stage non-small cell lung cancer (NSCLC);
2. Radical lobectomy is not performed;
3. Acception of any anti-tumor treatment before surgery (excluding Chinese medicine treatment);
4. Refused to enter the group or asked to leave the group.

Trial design

500 participants in 5 patient groups

RUL

Description:

patients who recieved the resection of right upper lobe (RUL)

Treatment:

Procedure: pulmonary lobectomy

RML

Description:

patients who recieved the resection of right middle lobe ()

Treatment:

Procedure: pulmonary lobectomy

RLL

Description:

patients who recieved the resection of right lower lobe (RML)

Treatment:

Procedure: pulmonary lobectomy

LUL

Description:

patients who recieved the resection of left upper lobe (LUL)

Treatment:

Procedure: pulmonary lobectomy

LLL

Description:

patients who recieved the resection of left lower lobe (LLL)

Treatment:

Procedure: pulmonary lobectomy