Androgens for Poor Responders in In Vitro Fertilization

Hospital Clinic of Barcelona

Status and phase: Completed; Phase 3

Conditions: Ovarian Response

Treatments: Drug: Transdermal testosterone

Study type: Interventional

Funder types: Other

Identifiers

NCT00693108

IVFANDROGENS

Details and patient eligibility

About

it has been shown that androgens in non human primates may favour follicular growth in the ovaries when animals are treated with gonadotropins which are the hormones used in patients receiving treatment with in vitro fertilization. Therefore, this study investigates the potential usefulness of testosterone treatment preceding gonadotropin administration in in vitro fertilization patients having a previous poor response to gonadotropins alone.

Sex: Female

Ages: 19 to 39 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients receiving the second IVF treatment attempt having the first treatment cycle cancelled because of poor ovarian response to gonadotropins

Exclusion criteria

• Previous ovarian surgery
• Clinical or laboratory profile suggesting premature ovarian failure

Trial design

0 participants in 2 patient groups

1

Experimental group

Description:

Transdermal testosterone treatment during the five days preceding gonadotropin therapy in IVF cycles

Treatment:

Drug: Transdermal testosterone

2

No Intervention group