Anesthesia During Neurophysiologic Monitoring in Scoliosis Patients

Nationwide Children's Hospital

Status: Completed

Conditions: Idiopathic Scoliosis

Treatments: Drug: Desflurane; Drug: propofol

Study type: Interventional

Funder types: Other

Identifiers

NCT01549873

IRB11-00727

Details and patient eligibility

About

When patients have spinal surgery, electrodes are placed on the body to measure motor evoked potentials (MEP) and somatosensory evoked potentials (SSEP). Many hospitals only use IV anesthesia because they feel that measuring MEP and SSEP is easier using IV anesthesia. At this hospital the investigators typically use inhaled anesthesia and are able to successfully measure MEP and SSEP. This is a study to find out if one method of anesthesia is better than the other for measuring MEP and SSEP.

Enrollment: 30 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with idiopathic scoliosis.

Exclusion criteria

• Patients with neuromuscular scoliosis.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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30 participants in 2 patient groups

Total intravenous anesthesia (TIVA)

Active Comparator group

Treatment:

Drug: propofol

Inhaled anesthesia

Active Comparator group

Treatment:

Drug: Desflurane