Anesthesia for Dental Treatment in Cardiac Patients: Lidocaine Comparative Study

University of Sao Paulo

Status: Completed

Conditions: Arrhythmias; Anxiety

Study type: Observational

Funder types: Other

Identifiers

NCT00669838

CAP432-03

Details and patient eligibility

About

Prospective, randomized double-blinded study to investigate hemodynamic changes in valvular cardiac patients during dental treatment with the use of a local anesthesia containing epinephrine.

Full description

Patients with valvular disease constitute a group in which local anesthesia must be effective to avoid higher release of endogenous catecholamines that could trigger hemodynamic. The study was conducted in the Dental Department of the Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (Brazil). Patients were allocated into two groups through an aleatory numbered table: PL (plain 2% lidocaine, n= 31) and LE (2% lidocaine with 1:100.000 epinephrine, n= 28). The anesthetic amount was registered. DIXTAL monitor (São Paulo- Brazil) captured blood pressure, heart rate, oxygenation and electrocardiogram records.

Enrollment: 59 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with acquired valvular disease

Exclusion criteria

• Patients having platelets counting lower than 70.000 or INR > 3

Trial design

59 participants in 2 patient groups

PL

Description:

Patients who receive local anesthesia with 2% lidocaine without epinephrine

LE

Description:

Patients who receive local anesthesia with 2% lidocaine with 1:100.000 epinephrine