Anesthetic Efficacy Of 4% ArtpharmaDent Versus 2% Mepecaine-L in Extraction of Lower First Primary Molars

Cairo University (CU)

Status: Unknown

Conditions: Badly Decayed Lower First Primary Molars in Children

Treatments: Drug: articaine; Drug: Mepivacaine 2% Injection

Study type: Interventional

Funder types: Other

Identifiers

NCT03942991

14422017496941

Details and patient eligibility

About

parallel technique will be done where the investigator (will be blinded) will give one type on anesthesia then performing the extraction and evaluating the intraoperative pain ,the same procedure will be done for the other type of anesthesia.

Enrollment: 20 estimated patients

Sex: All

Ages: 6 to 8 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Children aged 6-8 years.
• Medically fit (ASA I, II).
• Mentally capable of communication.
• Having a mandibular first primary molar tooth that require Extraction.
• Child must give assent prior to participation, as well as parental informed written consent.
• Body weight >20 kg.
• it should be the first dental treatment to the child

Exclusion criteria

• Medically and mentally compromised children.
• Children without a history of prolonged bleeding, platelet disorders, hypersensitivity,
• History of significant behavior management problems.
• Patients having active sites of pathosis in the area of injection.
• Patients who had taken analgesics or antibiotics in the 12-hrs preceding the injection.
• Patients allergic to Articaine and/or Mepivacaine and/or sulfur

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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20 participants in 2 patient groups

2% Mepecaine-L

Active Comparator group

Description:

infiltration injection of 2% Mepivacaine

Treatment:

Drug: Mepivacaine 2% Injection

4% Artpharmadent

Experimental group

Description:

infiltration injection of 4% Articaine

Treatment:

Drug: articaine