Aneuploidy Rate and Stimulation Protocol: Recombinant Follicle Stimulating Hormone (FSH) Versus Human FSH

IVI Madrid

Status: Terminated

Conditions: Aneuploidy Rate

Treatments: Procedure: Stimulation with human FSH; Procedure: Stimulation with recombinant FSH

Study type: Interventional

Funder types: Other

Identifiers

NCT01164943

MAD-FB-04-2010-01

Details and patient eligibility

About

Several stimulation protocols have been used in in vitro fertilization (IVF) in a cycle of egg donation; recombinant FSH and human FSH are included. The effect of each kind of hormone on aneuploidy rate it is unknown. If there was an increase on aneuploidy rate of one of these stimulation protocols, there will be a negative effect on the successful rates in the egg donation cycles. The aim of this study is to observe if there is a different in aneuploidy rate and morphological oocyte parameters between different stimulation protocols.

Enrollment: 80 patients

Sex: All

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Egg donation cycles with more than 8MII in oocyte retrieval day

Exclusion criteria

• Male factor
• Uterine malformations
• genetic alterations

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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80 participants in 2 patient groups

Human FSH

Active Comparator group

Treatment:

Procedure: Stimulation with human FSH

Recombinant FSH

Active Comparator group

Treatment:

Procedure: Stimulation with recombinant FSH