Angiogenesis in Early Breast Cancer for Prognosis Prediction

University of California Irvine (UCI)

Status

Completed

Conditions

Breast Lesions

Treatments

Procedure: magnetic resonance imaging

Study type

Interventional

Funder types

Other

Identifiers

NCT00599105

UCI-HS-2000-1141

NIH-CA90437

CBCRP-9WB-0020

Details and patient eligibility

About

This study will investigate the association of angiogenesis in breast cancer measured by magnetic resonance imaging and biomarkers with long-term prognosis of patients.

Enrollment

700 estimated patients

Sex

Female

Ages

18 to 90 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Patient with a breast mass highly suspicious for malignancy from clinical, mammographic or sonographic examination.
The study has been explained to the patient when she is scheduled for surgery.
Healthy normal volunteers for imaging protocol optimization.

Exclusion criteria

Pregnancy
Patients with implanted surgical clips (hemostatic clips) or other ferromagnetic material,
Patients engaged in occupations or activities which may cause accidental lodging of ferromagnetic materials, or who may have imbedded metal fragments from military activities,
Patients with metallic implants, because they may cause artifacts in diagnostic images due to magnetic field distortion,
Patients with implanted prosthetic heart valves,
Patients with pacemakers, neuro-stimulation devices,
A breast mass with features of benign tumor
The patients unwilling to participate in the study or fail to sign the consent form