Anodal TDCS and Postural Stability in Subacute Stroke

Riphah International University

Status: Completed

Conditions: Stroke

Treatments: Other: Anodal transcranial direct current stimulation; Other: Sham Stimulation

Study type: Interventional

Funder types: Other

Identifiers

NCT05903599

REC01353 Somia Shakeb

Details and patient eligibility

About

Stroke patients experience weakening of muscles on the affected side. Damage to the motor cortex and the pyramidal tract due to a stroke leads to a motor control disorders and co-contraction of trunk muscles due to abnormal levels of abdominal muscle tension and voluntary movement.

Full description

TDCS is known to modulate motor excitability in humans and motor performance is crucial in postural control. Studies reports that applying anodal TDCS to the ipsilesional motor cortex improved motor functioning in which the Transcranial Direct Current Stimulation may have stimulated preserved areas of the motor cortex to enhance synaptic efficiency along the corticospinal tract.

Anodal TDCS has been shown to have immediate and short-term effects in stroke but its long-term effects in stroke are still unclear. Additionally, the available literature focuses on acute and chronic stages of stroke so we will target subacute stage of stroke. Therefore, this study is designed to investigate the short and long-term effects of Anodal Transcranial Direct Current Stimulation on postural stability in subacute stroke.

Enrollment: 36 patients

Sex: All

Ages: 45 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Ischemic stroke
• Sub-acute stroke
• Minimum score of 18 on PASS

Exclusion criteria

Hearing and Visual loss/ deficit

• Recurrent CVA
• Neurological condition affects the cognition
• Wound at skull
• Presence of shunt and/or metallic implant at cranial region
• Brain tumors
• Musculoskeletal conditions/ surgery in the lower extremities
• Cognitively compromised

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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36 participants in 2 patient groups

Group A

Experimental group

Description:

anodal Transcranial direct current stimulation with saline soaked sponges will be used on electrodes, for 20 mins in addition to the 60 mins of conventional treatment.

Treatment:

Other: Anodal transcranial direct current stimulation

Group B

Sham Comparator group

Description:

A sham stimulation will be given. It will be comprised 20 min of sham TDCS followed by 60 mins of conventional treatment for postural stability in sub-acute stroke

Treatment:

Other: Sham Stimulation