Anomia Treatment Predictors

University at Buffalo (UB)

Status: Completed

Conditions: Anomia (Word-Finding Impairment); Aphasia

Treatments: Behavioral: Phonomotor Treatment (PMT); Behavioral: Phonological Components Analysis (PCA)

Study type: Interventional

Funder types: Other

Identifiers

NCT06619756

STUDY00008623

Details and patient eligibility

About

The goal of this clinical trial is to identify predictors of response to phonological-focused anomia treatment in people with aphasia. The main question it aims to answer is who responds to which type of anomia treatment. Researchers will compare Phonomotor Treatment and Phonological Components Analysis to see which treatment is more beneficial, and for whom. Participants will engage in both treatments over several months.

Full description

Participants will complete screening and characterization testing to determine eligibility for the study. Each treatment will be administered twice a week, for 10-15 sessions. Pre-treatment and post-treatment testing will also occur for each treatment. There will be a period of no treatment in between the first and second treatment blocks.

Enrollment: 2 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Chronic aphasia (6+ months)
• Anomia
• Sufficient auditory comprehension to follow task instructions
• Phonologic impairment

Exclusion criteria

• Progressive neurological illness or disease, including dementia
• Chronic medical illness that interferes with adherence to testing schedule
• Severe, uncorrected vision or hearing impairment that interferes with task completion
• Moderate-severe apraxia of speech or dysarthria that interferes with task completion

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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2 participants in 2 patient groups

PMT

Experimental group

Description:

Phonomotor Treatment (PMT) will be administered. This treatment improves anomia by training the sound sequences of words. This is a multimodal treatment approach that includes listening, producing, visualizing, and describing sounds and sound sequences. The participant practices the sound sequence tasks with the clinician.

Treatment:

Behavioral: Phonomotor Treatment (PMT)

PCA

Experimental group

Description:

Phonological Components Analysis (PCA) will be administered. This treatment improves anomia by identifying phonological features of words. A picture is presented. The participant provides features of the picture name: the first sound of the word, the final sound of the word, the number of syllables of the word, another word that starts with the same sound, and another words that rhymes with the word. The participant attempts to produce the word independently and by repeating after the clinician.

Treatment:

Behavioral: Phonological Components Analysis (PCA)