Antabuse in Severe Alcoholism: an Open Controlled Study

Psykiatrisk Center Gentofte

Status and phase: Unknown; Phase 4

Conditions: Alcoholism

Treatments: Drug: antabuse (disulfiram)

Study type: Interventional

Funder types: Other

Identifiers

NCT00431262

EudraCT no. 2006-004921-27

Details and patient eligibility

About

Newly detoxified alcoholics (N=60) are randomised to either antabuse (disulfiram) treatment or the control group for a total of 6 months.All patients will receive cognitive behavioural treatment in groups. The hypothesis to be tested is that more of the patients who receive antabuse (disulfiram) will be alcohol free during the 6 months treatment period compared to the control group. The trial is open.

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Alcoholism
• Living in the departments catchment area

Exclusion criteria

• Pregnancy
• Schizophrenia
• Bipolar disorder
• Other substance abuse
• Dementia
• Anorexia

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)