Antagonistic Interaction CB1-paracetamol

University Hospital, Clermont-Ferrand

Status and phase: Completed; Phase 1

Conditions: Pain

Treatments: Drug: Rimonabant and Paracetamol and placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT00750347

CHU-0037

Details and patient eligibility

About

Evaluation of an possible inhibiting effect of Rimonabant on the analgesic effect of Paracetamol in healthy volunteers

Full description

Double Blind, cross-over, randomized and controlled versus placebo, study in healthy volunteers.

Enrollment: 24 estimated patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy volunteers
• between 18 and 40 years old
• written consent given

Exclusion criteria

• Rimonabant or paracetamol hypersensibility
• Excessive consumption of alcohol, tobacco, coffee, tea or toxicomania
• Concomitant medication
• Chronical diseases

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind