Anterior Component Separation Versus Posterior Component Separation for Repair of Large Ventral Hernias

Zaza Demetrashvili

Status: Enrolling

Conditions: Large Midline Ventral Hernia

Treatments: Procedure: Posterior component separation; Procedure: Anterior component separation

Study type: Interventional

Funder types: Other

Identifiers

NCT03793738

01004006344

Details and patient eligibility

About

This study evaluates effect of anterior component separation and posterior component separation and transversus abdominis muscle release methods for treatment of midline ventral hernias.

Full description

The anterior component separation technique requires an extensive subcutaneous flap elevation, incision of the external oblique aponeurosis, and incision of the posterior rectus sheath.

The posterior component separation technique utilized the retromuscular space, accessed by incising the posterior rectus sheath and dissecting the posterior sheath between the internal oblique and transversus abdominis muscles. Transversus abdominis muscle release dissected the posterior sheath back to the transversus abdominal muscle and accessed the space between muscle and trasversalis fascia.

Enrollment: 40 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• subject has midline ventral hernia
• patient's approval to participate in the study

Exclusion criteria

• strangulated hernia
• patient's preference for either operative technique
• patient's refusal to participate in the study

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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40 participants in 2 patient groups

anterior component separation

Active Comparator group

Description:

The anterior component separation technique requires an extensive subcutaneous flap elevation, incision of the external oblique aponeurosis, and incision of the posterior rectus sheath.

Treatment:

Procedure: Anterior component separation

posterior component separation

Active Comparator group

Description:

The posterior component separation technique utilized the retromuscular space, accessed by incising the posterior rectus sheath and dissecting the posterior sheath between the internal oblique and transversus abdominis muscles.

Treatment:

Procedure: Posterior component separation