Anterior Quadratus Lumborum Block at the Lateral Supra-arcuate Ligament for Analgesia After Open Liver Surgery

University of Chinese Academy Sciences

Status: Completed

Conditions: Liver Surgery

Treatments: Procedure: Thoracic epidural analgesia; Procedure: Ultrasound-guided anterior quadratus lumborum block at the lateral supra-arcuate ligament

Study type: Interventional

Funder types: Other

Identifiers

NCT04668391

IRB-2020-350

Details and patient eligibility

About

This is a prospective, randomized, controlled, noninferiority trial for evaluating the efficacy of ultrasound-guided anterior quadratus lumborum block at the lateral supra-arcuate ligament versus thoracic epidural analgesia after open liver surgery.

Enrollment: 74 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age≥18 years
• ASA I-III
• Open liver surgery

Exclusion criteria

• Contraindication to nerve block or epidural puncture
• Chronic use of opioids or NSAIDs
• Refused to participate in the study

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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74 participants in 2 patient groups

Quadratus lumborum block

Experimental group

Description:

Ultrasound-guided anterior quadratus lumborum block at the lateral supra-arcuate ligament.

Treatment:

Procedure: Ultrasound-guided anterior quadratus lumborum block at the lateral supra-arcuate ligament

Thoracic epidural analgesia

Active Comparator group

Description:

Thoracic epidural analgesia at the level of T7-10.

Treatment:

Procedure: Thoracic epidural analgesia