Anterior Segment and Corneal Parameters in Keratoconus and High Myopic Astigmatism Using Schiempflug Imaging

Assiut University

Status: Not yet enrolling

Conditions: Keratoconus; High Myopia

Treatments: Other: pentacam scheimpflug tomography

Study type: Observational

Funder types: Other

Identifiers

NCT06739018

pentacam parameters compare

Details and patient eligibility

About

The purpose of this study was to compare Scheimpflug corneal tomography findings in keratoconus and high myopic astigmatic eyes, as well as to establish the parameters distinguishing keratoconus from high myopic astigmatism.

Full description

Keratoconus is a progressive, non-inflammatory corneal ecstatic disorder caused by alteration in the structure and organization of corneal collagen fibers. It results in uneven steepening of the cornea, resulting in irregular astigmatism that cannot be totally corrected with glasses, impairing the quality of life . However, in many cases, increased axial length adds to the myopic component of refractive error . Thereafter, keratoconus patients frequently have axial high myopia with irregular astigmatism . Furthermore, early diagnosis of keratoconus aids in the timely management of the condition, thus improving patients' quality of life. According to research, high myopia, in addition to the degree of astigmatism, is an alarming sign that requires further corneal assessment to rule out any corneal abnormalities such as keratoconus. Furthermore, keratoconus could be misdiagnosed as meridional amblyopia attributable to myopic astigmatism due to the lack of corneal tomography measurements . As a result, it is critical to evaluate all high myopia patients, particularly those considering refractive surgery, for high-risk corneas.

The criteria for diagnosing and classifying keratoconus are based on anterior corneal curvature data obtained using Placido-based corneal topography . Early alterations in eyes with keratoconus, however, have been found on the posterior corneal surface . Scheimpflug imaging uses a revolving Scheimpflug camera to determine the front and back surfaces of the cornea, hence measuring the overall thickness. Several studies have utilized Scheimpflug tomography to evaluate anterior segment parameters between normal eyes and eyes with keratoconus , but the utility of Scheimpflug imaging to distinguish between keratoconus and high myopic astigmatism has not been thoroughly examined.

Enrollment: 66 estimated patients

Sex: All

Ages: 15 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• keratoconus patient
• virgin clear cornea with high myopic astigmatism
• normal cornea with high myopic astigmatism

Exclusion criteria

• patients had previous ocular surgery
• ocular diseases rather than keratoconus
• contact lens wearer
• corneal opacity and corneal dystrophy

Trial design

66 participants in 2 patient groups

keratoconic group

Description:

patients with keratoconus

Treatment:

Other: pentacam scheimpflug tomography

high myopic astigmatim group

Description:

patients with high myopic astigmatism

Treatment:

Other: pentacam scheimpflug tomography