Anthropometric Measures and Severity of Gastroesophageal Reflux Disease

Ain Shams University

Status: Completed

Conditions: Gastroesophageal Reflux Disease

Study type: Observational

Funder types: Other

Identifiers

NCT01954667

Anthropometric Measures &GERD

Details and patient eligibility

About

evaluate the impact of different anthropometric measures on clinical and endoscopic severity of GERD and its relation to serum leptin.

Enrollment: 80 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Gastro esophageal reflux symptoms (e.g. heart burn, regurgitation, water brash or atypical symptoms such as hoarseness of voice, asthma and cough)
• complete upper gastrointestinal endoscopy.

Exclusion criteria

• Receiving medication for reflux disease (including proton pump inhibitor, histamine type 2 receptors blocker, prokinetic agents) in the previous month.
• Pregnant woman.
• History of upper abdominal surgery.
• Severe co-morbidity as cirrhosis, end-stage renal disease and heart failure.

Trial design

80 participants in 3 patient groups

obese and overweight

Description:

Group1 (n=30): overweight and obese (BMI ≥25 and/ or WHtR≥0.5)

average body weight

Description:

Group2 (n=30): normal weight (BMI ≥ 18 to \< 25 and/or WHtR ≥0.4 to \<0.5)

Control group

Description:

Control Group (n= 20): healthy subjects, matched for age and gender, were included in this study. All included controls had average weight (BMI ≥ 18 to \< 25 and/ or WHtR ≥0.4 to \<0.5)