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Anti-ageing Efficacy of a Cosmetic Formulation Containing NMN (2%) Versus Placebo

S

Seneque

Status

Completed

Conditions

Puffiness Around the Eyes
Fatigue
Wrinkle

Treatments

Other: Reference creme
Other: Test product creme

Study type

Observational

Funder types

Industry

Identifiers

NCT04685096
19E4487

Details and patient eligibility

About

The study aims at evaluating skin wrinkling, puffiness and fatigue and dark circle appearance on asian and african-american healthy volunteer cohorts receiving a cosmetic formulation containing NMN (2%). The product will be evaluated after 28 and 56 days of twice-daily application in comparison with a reference cosmetic formulation using clinical scoring under dermatological control. Cosmetic acceptability and future use will also be subjectively evaluated by analysis of the subjects answers to an evaluation questionnaire.

Enrollment

89 patients

Sex

Female

Ages

40 to 65 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Healthy subject
  • Subject having given her free informed, written consent
  • Subject willing to adhere to the protocol and study procedures
  • Subject with normal frontal temperature lower than 37.5°c/100.4°F
  • Subject has read and understood the information given by the investigator related to protection against Novel Coronavirus 19 and necessity to contact the investigator in case of any suspicion of COVID related manifestation (increase of frontal temperature, cough, sore muscles, weakness...) during the study

Exclusion criteria

  • Pregnant or nursing woman or woman planning to get pregnant during the study
  • Start, stop or change in hormonal treatment (including contraceptive pill) <1.5 months
  • Cutaneous pathology on the study zone (face)
  • Use of topical or systemic treatment during the previous weeks liable to interfere with the assessment of the cutaneous efficacy of the study product
  • Subject having undergone a surgery under general anesthesia within the previous month
  • Know allergy to certain cosmetic or dermato-pharmaceutic products
  • Subject having done injections on face and/or a lifting
  • Excessive exposure to sunlight or UV-rays within the month preceding the study

Trial design

89 participants in 2 patient groups

Asian skin
Description:
Twice-daily application for 55 Days
Treatment:
Other: Test product creme
Other: Reference creme
African-American skin
Description:
Twice-daily application for 55 Days
Treatment:
Other: Test product creme
Other: Reference creme

Trial contacts and locations

2

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Data sourced from clinicaltrials.gov

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