Anti-Ageing Health Supplement From Ginger Extracts

National University of Malaysia

Status

Completed

Conditions

Musculoskeletal

Cognitive Decline

Ageing Signs

Treatments

Dietary Supplement: ginger extract

Other: Placebo

Study type

Interventional

Funder types

Other

Identifiers

NCT06828783

UKM PPI/111/8-JEP-2022-395

Details and patient eligibility

About

This study examines the development and efficacy of a health supplement derived from ginger using water extraction. Designed to address aging-related issues such as muscle loss (sarcopenia) and cognitive decline, the capsule's safety and effectiveness were evaluated through clinical trials. Stability testing ensured the capsules maintained their quality under various environmental conditions. Clinical trials further assessed the supplement's antioxidant and anti-inflammatory properties. The findings support its potential benefits for elderly health and aging-related challenges.

Enrollment

90 patients

Sex

Male

Ages

48 to 63 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Healthy adult male
Blood chemistry results specifically Blood Urea Nitrogen (BUN), Serum Creatinine, Aspartate Aminotransferase (AST), Alanine Aminotransferase (ALT), Gamma-glutamyl transpeptidase (GGTP), Total Bilirubin and alkaline phosphatase and urinalysis results, specifically urine pH, protein, glucose, ketone, and bilirubin levels within +/- 20% of normal value indicated in the lab report.
Individuals are willing to maintain their exercise habits and dietary patterns throughout the trial
No allergy to ginger
Provide written informed consent before screening
Subject is willing and able to comply with the study visit schedule and procedure, geographic proximity (investigator's discretion) that allows adequate follow-up
Subjects understand the study protocol and sign informed consent forms

Exclusion criteria

Use of dietary supplements within one week of Day 0. Supplements include any ginger (Zingiber officinale, ginger root, black ginger, zingiberis rhizoma) vitamins, minerals, and herbal products, including herbal drinks.
Presence of, or clinically significant history of, cancer, cardiovascular, endocrine, kidney, liver, lung, gastrointestinal, metabolic disorder, absorption disorder such as Celiac or Crohn's disease and/or any other chronic health condition such as diabetes identified from the findings of the interview.
Presence of gallstones or history of gallbladder disease.
Presence or history of diabetes.
Presence of cardiovascular disease and hypertension with inconsistent medication regimen, unstable conditions, and without proper physician's - Ten hours before the blood and urine sample collection, subjects should refrain from using medications such as statins (e.g., simvastatin, fluvastatin), NSAIDS including paracetamol, aspirin, nitric oxide (eNOS) activators or inhibitors (e.g., selegiline, Viagra), and angiotensin II receptor blocker (e.g., Telmisartan (blood pressure)) or take any of these medications
Subjects with vegan diet
Current smoker or used to smoke in the past 3 months
Subject for surgery or had undergone surgery in the past 3 months History of bleeding tendencies or any condition predisposing to bleeding e.g. thrombocytopenia, abnormal liver function, liver disease (e.g. chronic hepatitis), gastrointestinal ulcers
Subjects who have significantly changed their physical activity in the past 2-4 weeks or who intend to change them during the study
Participation in another clinical trial within 30 days of enrolment into the study.
History or current abuse of nicotine, drugs, or alcohol, or intake > 3 alcoholic beverages per day