Anti-E1E2 (D32.10 Epitope-binding) Antibodies Status Prior Therapy Favors Direct-acting Antiviral Treatment Efficacy

Civil Hospices of Lyon

Status: Completed

Conditions: Chronic Hepatitis c

Treatments: Drug: Direct-acting antiviral therapy

Study type: Observational

Funder types: Other

Identifiers

NCT03348059

CRC_GHN_2017_005

Details and patient eligibility

About

The hypothesis was to check whether baseline anti-E1E2 antibodies could predict virological outcome in Hepatitis C virus (HCV)-infected patients receiving direct-acting antiviral treatment

Full description

Presence of anti-E1E2 antibodies was previously associated with spontaneous cure of hepatitis C virus (HCV). The hypothesis was to check whether baseline anti-E1E2 antibodies could predict virological outcome in HCV-infected patients receiving direct-acting antiviral treatment

Enrollment: 103 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18 years of age or older
• HCV patients treated with direct-acting antiviral treatment
• Patients with a prior treatment blood sample
• Patients with sustained virological response or virological relapse

Exclusion criteria

• HIV or hepatitis B virus (HBV) coinfection