Anti-Helicobacter Pylori Antibodies (IgG) in Serum of Women With Unexplained Infertility

A

Ain Shams Maternity Hospital

Status

Completed

Conditions

Infertility, Female

Study type

Observational

Funder types

Other

Identifiers

NCT02684604
unexplained infertility

Details and patient eligibility

About

Prevalence of anti-H.pylori IgG in serum of women with unexplained infertility and comparing that with it's prevalence in fertile women.

Full description

Unexplained infertility was diagnosed according to standard World Health Organization (WHO) criteria. All women in the study had hormonal assessment to evaluate their ovulatory cycles, thyroid function, circulating prolactin and androgen levels. The ovarian reserve was checked by measurement of serum FSH and an antral follicle count on the third day of the menstrual cycle. Screening for infertility also included transvaginal ultrasound and hysterosalpingography, to exclude possible uterine malformations or pathologies, and to assess the patency of the fallopian tubes. Male factor infertility was excluded in all couples, according to standard WHO semen analysis. Following admission, all patients underwent complete clinical examination and detailed medical history was obtained. A venous sample was collected to test serum for HP IgG seropositivity by enzyme linked immunoassay for HELICOBACTOR PYLORI IgG (ENZYME IMMUNOASSAY TEST KIT).

Enrollment

88 patients

Sex

Female

Ages

18 to 35 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  1. regular cycles.
  2. normal thyroid function, prolactin and androgen levels.
  3. normal semen analysis of the partner.
  4. normal hysterosalpingography.
  5. normal transvaginal ultrasound examination.

Exclusion criteria

  1. possible uterine malformations or pathologies.
  2. presence of infections, including hepatitis, human immunodeficiency virus (HIV), TORCH, Chlamydia trachomatis and Mycoplasma.
  3. presence of anti-sperm antibodies in serum.
  4. Male factor infertility.

Trial design

88 participants in 2 patient groups

unexplained infertility patients
Description:
44 patients diagnosed to have unexplained infertility
Fertile women
Description:
44 fertile women

Trial contacts and locations

0

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2024 Veeva Systems