Anti-Mullerian Hormone Changes After Laparoscopic Ovarian Cystectomy for Endometrioma Compared With the Non-ovarian Conditions

Thammasat University

Status: Unknown

Conditions: Ovarian Reserve

Study type: Observational

Funder types: Other

Identifiers

NCT01919333

MTU-OB-3-096/56

Details and patient eligibility

About

This aim of the study is to evaluate the impact of endometrioma and laparoscopic cystectomy on ovarian reserve as measured by serum antimullerian hormone and to study the different effects of levels of serum antimullerian hormone between laparoscopic cystectomy and the non-ovarian pelvic surgery.

Enrollment: 56 estimated patients

Sex: Female

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• • Participants must be between the ages of 18 - 45 during enter the study .

  • Every participants have to completely understand the process of this study and have written informed consent .
  • Having regular menstrual cycles (21-35 days) at the time of operation
  • no evidence of any other endocrine disorders such as diabetes mellitus, thyroid dysfunction, hyperprolactinemia, congenital adrenal hyperplasia, Cushing's syndrome, or adrenal insufficiency.
  • undergo laparoscopic ovarian cystectomy or laparoscopic non- ovarian pelvic surgery for benign pelvic disease
  • No previous history of adnexal surgery
  • No any suspicious findings of malignant ovarian diseases
  • Never taking any medication such as oral pill and hormonal drugs within 3 months before the enrollment.
  • pathological diagnosis of excised ovarian tissue confirm as endometriotic cyst in study group and other benign pelvic disease in control group

Exclusion criteria

• polycystic ovarian syndrome according to the Rotterdam criteria

  • pathological report as the malignant diseases
  • have operation conversion to open-laparotomy

Trial design

56 participants in 2 patient groups

laparoscopic ovarian cystectomy

Description:

the group who laparoscopic ovarian cystectomy are performed for endometrioma

laparoscopic non- ovarian pelvic surgery

Description:

the group whom laparoscopic non- ovarian pelvic surgery are performed