Anti-obesity Effects of Dandelion (Taraxacum Officinale L.)

October 6 University

Status: Completed

Conditions: Obese Women; Perimenopause

Treatments: Dietary Supplement: The dandelion extract; Drug: Xenical

Study type: Interventional

Funder types: Other

Identifiers

NCT06625736

Dandelion effect on obesity

Details and patient eligibility

About

The study investigates the effectiveness of the natural product Dandelion in treating obesity in premenopausal women through a randomized interventional trial, measuring various parameters and biomarkers.

Full description

The study aims to explore the anti-obesity effects of dandelion supplementation in premenopausal obese women. The research will measure changes in appetite, energy intake, body weight, composition, lipid profile, and inflammatory markers, providing evidence of dandelion's efficacy as an anti-obesity phototherapy. The randomized interventional trial will measure multiple parameters and biomarkers.

Enrollment: 120 patients

Sex: Female

Ages: 18 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Premenopausal women with obesity. Age between 18-45 years Stable body weight in the past 3 months

Exclusion criteria

Pregnancy Breastfeeding Diabetes Cardiovascular diseases kidney or liver diseases use of medications that affect body weight Smoking Allergy to dandelion or related plants

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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120 participants in 2 patient groups

Control group

Active Comparator group

Description:

The Xenical group:60 patients will receive identical capsules of 120mg (one capsule) to be taken three times daily with meals and for 12 weeks, equaling 360mg total daily dose.

Treatment:

Drug: Xenical

The dandelion extract group

Experimental group

Description:

The dandelion extract group: 60 patients will receive 500 mg capsules of dandelion leaf extract, given 3 times per day before meals and for 12 weeks.

Treatment:

Dietary Supplement: The dandelion extract