Anti-VEGF Instead of Intraoperative Fan-shaped Photocoagulation in BRVO Combined With Vitreous Hemorrhage

W

Wenzhou Medical University

Status

Unknown

Conditions

Vitrectomy
Anti-VEGF
Branch Retinal Vein Occlusion

Treatments

Procedure: anti-VEGF
Procedure: fan-shaped photocoagulation

Study type

Interventional

Funder types

Other

Identifiers

NCT03637283
10008 (Registry Identifier)

Details and patient eligibility

About

To evaluate the efficacy and safety of Anti-VEGF instead of intraoperative fan-shaped photocoagulation in BRVO combined with vitreous hemorrhage.

Enrollment

100 estimated patients

Sex

All

Ages

18 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Age ≥ 18 years old;
  • BRVO is diagnosed
  • Vitreous hemorrhage
  • Vitreous hemorrhage combined with mild retinal fibrovascular proliferation (early fibrous vascular membrane, thin fibrous vascular membrane, loose retinal adhesion and intact local retinal structure)

Exclusion criteria

  • BRVO combined with severe retinal fibrovascular proliferation (long-term fibrovascular membrane, thick fibrous vascular membrane and tightly attached to the retina, deformation of local retinal, retinal tear or suspension of retinal vein )
  • BRVO combined with retinal detachment
  • Retinal veins are completely whitened
  • iris neovascularization or neovascular glaucoma
  • Combined glaucoma
  • combined with other retinopathy
  • Received anti-VEGF treatment within 3 months before surgery

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

100 participants in 2 patient groups

anti-VEGF
Experimental group
Description:
vitreoretinal surgery combined with intraoperative anti-VEGF
Treatment:
Procedure: anti-VEGF
fan-shaped photocoagulation
Active Comparator group
Description:
vitreoretinal surgery combined with fan-shaped photocoagulation
Treatment:
Procedure: fan-shaped photocoagulation

Trial contacts and locations

0

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Central trial contact

Wei Lin, M.D; Yong Wei, M.D

Data sourced from clinicaltrials.gov

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