Antibacterial Effect of Miswak Toothpaste Compared to Fluoride Toothpaste

Cairo University (CU)

Status: Unknown

Conditions: Caries

Treatments: Other: Miswak toothpaste; Other: Fluoride toothpaste

Study type: Interventional

Funder types: Other

Identifiers

NCT05109299

miswak

Details and patient eligibility

About

Meswak is scientifically formulated herbal toothpaste with pure extract of the Miswak plant 'Salvadore Persica', the famous 'Toothbrush Tree' used for centuries. The astringent and anti-bacterial properties of Meswak helps reduce tooth decay , fight plaque and prevent gum diseases. Miswak Herb is a rare, potent, priceless, wonder herb that delivers incredible Dental Care benefits.

Full description

This study is a randomized clinical trial, with parallel study design, 1:1 allocation ratio and superiority framework. The aim of the current trial is to evaluate antibacterial effect miswak toothpaste compared to fluoride toothpaste in high caries risk patients.

Enrollment: 32 estimated patients

Sex: All

Ages: 18 to 25 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• High caries risk patients.
• At least one carious tooth according to CAT caries risk assessment model.
• Patient compliance

Exclusion criteria

• Participant in another trial.
• Using another antimicrobial agents since one month of sampling.
• Systemic diseases or concomitant medication affecting salivary flow.
• Parafunctional habits.
• Pregnancy.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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32 participants in 2 patient groups

Miswak toothpaste

Experimental group

Description:

Dabur meswak herpal toothpaste

Treatment:

Other: Miswak toothpaste

Fluoride toothpaste

Active Comparator group

Description:

Signal fluoride toothpaste, containing 1450 ppm of fluoride

Treatment:

Other: Fluoride toothpaste