Antibacterial Effect of New Herbal Paste Used as an Intracanal Medication

Nahda University

Status and phase: Enrolling; Phase 3

Conditions: Infection Primary

Treatments: Drug: herbal intracanal medication paste; Drug: Meta paste

Study type: Interventional

Funder types: Other

Identifiers

NCT05657132

050622

Details and patient eligibility

About

studying the antibacterial effect of Cosuts paste as an intracanal medication against Enterococcus faecalis that present in necrotic primary teeth

Full description

The children were randomly divided into two groups (I, II) Group I (N=12): using Costus-based paste as an intracanal medicament. Group II (N= 12): Calcium hydroxide iodoform paste (Metapex) as an intracanal medicament.

Procedure:

Access opening was started. then a swab was taken from the distal root canal with a dry paper point and transferred to a sterile test tube. The canals were filled with an intracanal medication according to the patient group. In group I, the canals was filled with a previously prepared Costus-based paste for one week, and In Group II, the canals were filled with Meta paste for one week. After 1 week, the paste was washed away from the canals then another swab was taken from the distal canal by a dry paper point as done before preoperatively.

The 2 swabs were transferred within 2 hours to the lab for bacterial culture and detection of enterococcus faecalis count.

Enrollment: 24 estimated patients

Sex: All

Ages: 4 to 10 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients with clinically and radiologically diagnosed infected primary teeth in their mandibular arch.
• Teeth should be deeply carious, with a history of spontaneous pain and carious exposures with necrotic pulp was also be selected
• radiographic evidence of adequate alveolar bone support, and absence of internal or external resorption.
• tooth must be restorable.

Exclusion criteria

• vital tooth
• Non restorable teeth

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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24 participants in 2 patient groups

Costus paste

Experimental group

Description:

Costus paste used as an intracanal medication for decreasing the number of enterococcus faecalis present in the necrotic root of the primary molar

Treatment:

Drug: herbal intracanal medication paste

metapaste

Active Comparator group

Description:

metapaste used as an intracanal medication for decreasing the number of enterococcus faecalis present in the necrotic root of the primary molar

Treatment:

Drug: Meta paste