Antibacterial Effect of Ozonated Olive Oil, Propolis and Chlorhexidine Mouthwashes in Pediatric Patients

Alexandria University

Status: Completed

Conditions: Oral Hygiene; Oral Health

Treatments: Other: Chlorhexidine; Other: Ozonated olive oil; Other: Propolis

Study type: Interventional

Funder types: Other

Identifiers

NCT07197073

0937_07/2024

Details and patient eligibility

About

Streptococcus mutans and Lactobacillus acidophilus are the most common cariogenic microorganisms. Chlorhexidine has been the most widely used antibacterial mouthwash in dentistry. On the other hand, few studies have reported the antibacterial potential of Propolis and Ozonated olive oil as antibacterial agents that can be used as alternatives to Chlorhexidine. This study aims to evaluate and compare the antibacterial effect of Ozonated olive oil, Propolis, and Chlorhexidine on S. mutans and L. acidophilus count in pediatric patients.

Enrollment: 51 patients

Sex: All

Ages: 8 to 12 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• High caries risk patients, according to AAPD guidelines, with visible caries or radiographic penetration into dentin, white spots on smooth surfaces, or recent restorations or missing teeth due to caries.
• Cooperative children according to Frankl's rating (score 3 & 4)

Exclusion criteria

• Children with any medical illness or oral infection or those who received any type of antibiotic treatment or mouthwash for two weeks before or during the study were excluded

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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51 participants in 3 patient groups

Ozonated olive oil mouthwash

Experimental group

Treatment:

Other: Ozonated olive oil

Propolis mouthwash

Experimental group

Treatment:

Other: Propolis

Chlorhexidine mouthwash

Active Comparator group

Treatment:

Other: Chlorhexidine