Antibiotic Prophylaxis in Mesh Repair of Inguinal Hernias

Diskapi Teaching and Research Hospital

Status and phase: Completed; Phase 4

Conditions: Inguinal Hernia

Treatments: Drug: sefazolin

Study type: Interventional

Funder types: Other

Identifiers

NCT01264003

DEAH-1002-IHR

Details and patient eligibility

About

Inguinal hernia repairs is clean surgical procedures. However infection may be a concern when prosthetic materials are used. This prospective randomized study has been set to observe if antibiotic prohylaxis is of benefit in mesh repair of inguinal hernias.

Full description

There are two group in the study. Control group received no antibiotic prohylaxis, whereas a single dose 1 gr. intravenous cefazoline is given to the patient in prophylaxis arm of the study. 30-days surgical site infection rates and 1 year prosthetic intervention late infection rates are observed and recorded. Side effects of antibiotic used are also recorded.

Enrollment: 200 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: inguinal hernia repair -

Exclusion Criteria: uncontrolled diabetes mellitus,

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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200 participants in 1 patient group

1

Active Comparator group

Description:

Antibiotic prohylaxis / Lichtenstein repair

Treatment:

Drug: sefazolin