Antibodies and Immunity After Vaccination of Recovered Patients With COVID-19 and Long COVID-19 Symptoms

Mahidol University

Status: Active, not recruiting

Conditions: Long COVID-19

Study type: Observational

Funder types: Other

Identifiers

NCT05484700

1013/2564(IRB3)

Details and patient eligibility

About

We investigated the association between immune system responsibilities in Long COVID patients and Full recovery patients.

Full description

This retrospective cohort study compared immunogenicity post COVID-19 between individuals (aged 18-65 years and had confirmed SARS-CoV-2 infection from January to May 2022 ) with residual Long COVID-19 symptoms (LC) and ones with full recovery (Full) related to pathophysiology, immunology and clinical consequence.

Enrollment: 305 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Long COVID group; at longer than 1-month post COVID-19 based the presence of one of the three following symptoms: fatigue/myalgia, breathlessness, and anorexia
• Full recovery group; patients with asymptomatic symptoms
• post COVID-19 they had not received any additional COVID vaccine

Exclusion criteria

• people who received additional vaccination after leaving quarantine before the day of the immunization test
• pregnant patients,
• people who had a history of allergic reactions after COVID-19 vaccination or any drugs