Anticholinergic Risk Scale and Resource Use After Elective Noncardiac Surgery

Ottawa Hospital Research Institute

Status: Completed

Conditions: Length of Stay; Aged; Epidemiology; Anti Cholinergics; Surgical Procedure, Operative

Treatments: Other: anticholinergic risk scale

Study type: Observational

Funder types: Other

Identifiers

NCT03151616

DM6

Details and patient eligibility

About

This study investigates the association of preoperative anticholinergic medication exposure with healthcare resource utilization in a population-based sample of older patients enrolled in a universal pharmacare program

Full description

Multilevel multivariable regression analysis will be used to investigate the adjusted association between preoperative Anticholinergic Risk Scale and postoperative healthcare resource utilization. Sensitivity analyses will be used to evaluate the robustness of the primary analysis.

Enrollment: 244,976 patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• at least 66 years old on the day of surgery
• Intermediate to high risk elective noncardiac surgery

Exclusion criteria

Trial design

244,976 participants in 3 patient groups

No anticholinergic exposure

Description:

People with an anticholinergic risk scale score of 0

Moderate anticholinergic exposure

Description:

People with an anticholinergic risk scale score of 1-2

Treatment:

Other: anticholinergic risk scale

High anticholinergic exposure

Description:

People with an anticholinergic risk scale score of \>=3

Treatment:

Other: anticholinergic risk scale