Anticoagulant/Antiaggregant Use and Postoperative Bleeding Risk in Patients With Bladder Tumor and Benign Prostatic Hyperplasia

Bezmialem Vakif University

Status: Completed

Conditions: Operative Bleeding; Blood Transfusion Complication; Hematuria; Retention, Urinary

Study type: Observational

Funder types: Other

Identifiers

NCT05314582

196083

Details and patient eligibility

About

Patients who were using anticoagulant or antiaggregant medications for any reason and underwent transurethral resection of bladder tumor (TUR-BT) or transurethral resection of the prostate (TURP) or open prostatectomy (OP) due to BPH will be compared with those who were not using anticoagulant or antiplatelet medication. The rates of postoperative clot retention, presence of hematuria, reoperation due to hematuria, blood transfusion and re-admissions due to hematuria in the first postoperative month will be compared.

Enrollment: 500 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients undergoing complete endoscopic transurethral tumor resection (TUR-BT) for bladder cancer
• Patients undergoing TURP due to benign prostatic hyperplasia
• Patients undergoing open prostatectomy due to benign prostatic hyperplasia

Exclusion criteria

• Patients who underwent incomplete transurethral tumor resection for bladder cancer
• Patient who underwent TUR biopsy for restaging with no obvious macroscopic tumoral lesion
• Patients who underwent cystectomy for bladder cancer

Trial design

500 participants in 6 patient groups

TURP patients using anticoagulant/antiaggregant medication

Description:

Patients who used anticoagulant/antiaggregant medication for any reason (eg: coronary artery disease, atrial fibrillation, cerebrovascular disease) before surgery and underwent endoscopic prostatectomy (TURP).

TURP patients not using anticoagulant/antiaggregant medication

Description:

Patients with no history of anticoagulant/antiaggregant medication and underwent endoscopic prostatectomy (TURP).

TUR-BT patients using anticoagulant/antiaggregant medication

Description:

Patients who used anticoagulant/antiaggregant medication for any reason (eg: coronary artery disease, atrial fibrillation, cerebrovascular disease) before surgery and underwent endoscopic bladder tumor resection (TUR-BT).

TUR-BT patients not using anticoagulant/antiaggregant medication

Description:

Patients with no history of anticoagulant/antiaggregant medication and underwent endoscopic bladder tumor resection (TUR-BT).

Open prostatectomy patients using anticoagulant/antiaggregant medication

Description:

Patients who used anticoagulant/antiaggregant medication for any reason (eg: coronary artery disease, atrial fibrillation, cerebrovascular disease) before surgery and underwent open prostatectomy (OP).

Open prostatectomy patients not using anticoagulant/antiaggregant medication

Description:

Patients with no history of anticoagulant/antiaggregant medication and underwent open prostatectomy (OP).