Antiemetic Effect of the Addition of Ondansetron to the Morphine Solution in Patient-Controlled Analgesia (PCA)

Khon Kaen University

Status: Completed

Conditions: Postoperative Nausea and Vomiting

Treatments: Drug: ondansetron adding in PCA

Study type: Interventional

Funder types: Other

Identifiers

NCT00199329

I48027

Details and patient eligibility

About

PCA morphine always introduces nausea and vomiting during the postoperative period. Ondansetron can reduce PONV (postoperative nausea vomiting). We, the researchers at Khon Kaen University, are trying to add ondansetron in PCA morphine. Patients receive a small dose of ondansetron when they request morphine.

Enrollment: 160 patients

Sex: All

Ages: 15 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age between 15-60 years old

Exclusion criteria

• History of motion sickness, smoking

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind