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Antihypertensive Therapy in Patients With Comorbidities

C

Center of Personalized Medicine, Pirogova

Status

Unknown

Conditions

Adherence to Personalized EBM Antihypertensive Drug Prescriptions for Patients With Hypertension and Comorbidities in Everyday Clinical Practice

Treatments

Drug: antihypertensive therapy

Study type

Observational

Funder types

Other

Identifiers

NCT04791046
20210308

Details and patient eligibility

About

A retrospective analysis

Full description

This retrospective study will be performed using all-Russian nationwide database of anonymized medical health claims and administrative data. The database holds information on diagnoses, patient data, medications, results of examinations, laboratory values, and genomic information, visits, follow up and outcomes. Participating health care organizations include a mix of hospital, primary care, and specialty treatment providers spanning a wide range of geographies, age groups, and income levels.

This study will analyze of outcomes according to comorbidity and antihypertensive drug prescriptions. The study will include patients who were first diagnosed with hypertension, attended the hospital as an outpatient due to hypertension, and received their antihypertensive prescription as an outpatient. To be eligible for inclusion, patients must have had comorbidities and outpatient visits or hospitalizations (for any indication) during the 3-years. The study will focused on comorbidities for choice of antihypertensive drug therapy: diabetes mellitus, dyslipidemia, gout/hyperuricemia, heart diseases, cerebrovascular diseases, and renal diseases.

We going to analyze the EMR of patients who had hypertension and comorbidities by CDSS (MedicBK) utilizing a core laboratory.

Enrollment

100,000 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

patients who were first diagnosed with hypertension, attended the hospital as an outpatient due to hypertension, and received their antihypertensive prescription as an outpatient. To be eligible for inclusion, patients had to have comorbidities and outpatient visits or hospitalizations (for any indication) during the 3-years.

Exclusion criteria

No

Trial design

100,000 participants in 2 patient groups

By CDSS (MedicBK) Analysis
Treatment:
Drug: antihypertensive therapy
General practice
Treatment:
Drug: antihypertensive therapy

Trial contacts and locations

1

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Central trial contact

Svetlana Kozlova, MD; Evgeny Pokushalov, Prof. MD PhD

Data sourced from clinicaltrials.gov

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